ACoP10

Applied BioMath Presentations and Posters

We're excited to attend ACoP10! Listed below are the presentations and posters we will present. Additionally, we will have a booth at the conference. 

Monday, October 21

11:00am-12:15pm

"Integrated Pharmacometrics and Sytems Pharmacology (iPSP) Modeling Without Borders: Opportunities and Challenges for Re-purposing iPSP Models"

Co-Chaired by: Dan Kirouac, PhD, Senior Principal Scientist, Applied BioMath

Tuesday, October 22

3:30pm-5:00pm

"Translational modeling strategies to predict clinical starting and efficacious doses for CD3 bispecific molecules"

Presented by: Alison Betts, Senior Director, Scientific Collaborations, Fellow of Modeling and Simulation

Wednesday, October 23

10:45am-12:15pm

"QSP model of mRNA lipid nanoparticle for preclinical to clinical translation"

Presented by: Joshua Apgar, PhD, Co-Founder & CSO, Applied BioMath

3:45pm-5:15pm

"An overview of quantitative evaluation methods for QSP models"

Presented by: Helen Moore, PhD, Director of Applied Mathematics, Applied BioMath

Thursday, October 24

7:00am-12:00pm

"Quantitative Systems Pharmacology in Translational Drug Development"

Co-Presented by: John Burke, PhD, Co-Founder, President and CEO, Applied BioMath

Monday, October 21

M-078

"A semi-mechanistic PK/PD model of CX3CR1 and fractalkine to support the development of BI 655088"

Primary author: Joshuaine Grant, MSc, MBA, Senior Principal Scientist, Applied BioMath

Presented by: John Burke, PhD, Co-founder, President and CEO, Applied BioMath

Tuesday, October 22

T-083

"Applying Metropolis-Hastings sampling to QSP model to understand the variability in individual animal responses to anti-CTLA4 in CT26 syngeneic mouse model"

Presented by: Lin Lin, PhD, Principal Scientist, Applied BioMath

T-084

"A population QSP model to capture individual tumor growth inhibition responses to anti-CTLA4 therapy in CT26 syngeneic mouse model"

Presented by: Alison Betts, Senior Director, Scientific Collaborations and Fellow of Modeling and Simulation, Applied BioMath

Wednesday, October 23

W-080

"Dynamic-TMDD: A Pharmacokinetic Modeling framework for Immuno-Oncology"

Presented by: Dan Kirouac, PhD, Senior Principal Scientist, Applied BioMath

W-089

"A quantitative systems pharmacology (QSP) model for Abeta pathway to predict effect of aducanumab on Abeta SUVR change"

Presented by: John Burke, PhD, Co-founder, President and CEO, Applied BioMath