June 25 - 26, 2020
Applied BioMath Presence
Presentation: Targeting Bispecific Antibodies and Developing Systems Disease Models in I/O
Presentation Time: June 25th at 12:55PM
- Systems pharmacology is a mathematical modeling and engineering approach to translational medicine that quantitatively integrates knowledge about therapeutics with an understanding of its mechanism of action in the context of human disease mechanisms.
- Several examples will be shown that highlight mathematical modeling efforts to accelerate the discovery and development of best-in-class therapeutics and impact critical decisions, in the continuum from preclinical exploration to clinical research.
- Examples include, T cell engager at the new target through lead generation stage, GITR-mediated T cell dynamics, species translation to make human predictions, and mechanistic predictions in checkpoint inhibitors.
Presenter: John M. Burke, PhD, Co-Founder, President and CEO, Applied BioMath