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News

Applied BioMath, LLC Announces Participation at PEGS: The Essential Protein Engineering Summit

Applied BioMath (www.appliedbiomath.com), the industry-leader in applying mechanistic systems modeling, simulation, and analysis to de-risk drug research and development, today announces their upcoming participation at PEGS: The Essential Protein Engineering Summit being held April 30 - May 4, 2018 in Boston, MA. Applied BioMath is sponsoring, exhibiting, presenting a poster, and presenting two talks at the conference.

Applied BioMath, LLC Announces Collaboration with Checkpoint Therapeutics for Semi-Mechanistic Pharmacokinetic and Pharmacodynamic Modeling in Immuno-Oncology

Applied BioMath (www.appliedbiomath.com), the industry-leader in applying mechanistic mathematical modeling, simulation, and analysis to de-risk therapeutic research and development, today announced a collaboration with Checkpoint Therapeutics, Inc., for semi-mechanistic pharmacokinetic and pharmacodynamic (PK/PD) modeling in advanced metastatic solid tumors.   

Applied BioMath, LLC Collaborates with Xencor for Semi-Mechanistic PK/PD Modeling of XmAb®24306, Xencor's Lead IL15 Program for the Treatment of Solid Tumors

Applied BioMath (www.appliedbiomath.com), the industry-leader in applying mechanistic modeling, simulation, and analysis to de-risk drug research and development, today announced a collaboration with Xencor to perform semi-mechanistic PK/PD modeling to analyze Xencor's XmAb® IL15/IL15Rα-Fc program for the treatment of solid tumors.  The collaboration will focus on developing a mathematical model relating XmAb®24306 modulated potency and extended half-life to observed pharmacokinetics and in vivo T-cell stimulation.

Applied BioMath, LLC Announces Collaboration with Pandion Therapeutics for Semi-Mechanistic Pharmacokinetic and Target Occupancy Modeling in Autoimmune Disease

Applied BioMath (www.appliedbiomath.com), the industry-leader in applying mechanistic modeling, simulation, and analysis to accelerate and de-risk drug research and development, today announced a collaboration with Pandion Therapeutics for semi-mechanistic pharmacokinetic and target occupancy (PK/TO) modeling in Autoimmune Disease.

Applied BioMath, LLC Announces Pharmacokinetic and Pharmacodynamic Modeling Collaboration with Compass Therapeutics

Applied BioMath (www.appliedbiomath.com), the industry-leader in applying mechanistic modeling to drug research and development, today announced a collaboration with Compass Therapeutics for the semi-mechanistic pharmacokinetic and pharmacodynamic (PK/PD) modeling of a therapeutic targeting solid tumors.  Semi-mechanistic PK/PD models will be developed for mouse, cynomolgus monkey, and human species and will help answer strategic questions such as the target coverage required for efficacy and dose regimen selection for the clinical study.

Registration is Open for QSP Industry & Academia Symposium

The QSP Industry & Academia Symposium is a seminar series for presenting, learning, and discussing topics relevant to quantitative systems pharmacology (QSP).The goal of this event is to foster an active community of industry and academic participants interested in these topics, and create a forum for sharing of successes and challenges.

Applied BioMath, LLC to Present at the Annual Drug Development Boot Camp`

Applied BioMath (www.appliedbiomath.com), the industry-leader in applying mechanistic modeling to drug research and development, today announced their participation at the annual Drug Development Boot Camp November 15-16, 2017 at the Harvard Club in Boston, MA. The Drug Development Boot Camp is hosted by Speid & Associates, Inc., in coordination with Harvard's Office of Technology Development, and is a two-day intensive program for executive-level individuals that involves hands-on learning about the drug development process.

Applied BioMath, LLC Announces Collaboration with Syntimmune for Pharmacokinetic and Pharmacodynamic Modeling in Clinical Program for Autoimmune Diseases

Applied BioMath® (www.appliedbiomath.com), the industry leader in applying mechanistic modeling to drug research and development, today announced a collaboration with Syntimmune to provide semi-mechanistic pharmacokinetic and pharmacodynamic (PK/PD) modeling for Syntimmune's ongoing clinical trials.  Applied BioMath will deploy its Model-Aided Drug Invention (MADI) to analyze clinical data from Syntimmune's lead drug candidate, SYNT001.

Applied BioMath, LLC to Sponsor and Present at Antibody Engineering and Therapeutics Conference

Applied BioMath (www.appliedbiomath.com), the industry-leader in applying mechanistic modeling to drug research and development, today announced their participation at the Antibody Engineering and Therapeutics Conference December 11-15, 2017 in San Diego, CA. John Burke, PhD, will present Model Aided Drug Invention (MADI) case studies on Thursday, December 14, 2017 at 12:00 p.m. In addition to speaking at the event, Applied BioMath is also participating as a scientific briefing sponsor. 

Applied BioMath, LLC to Present Case Studies on Model-Aided Drug Invention (MADI) at the American Conference of Pharmacometrics (ACoP)

Applied BioMath (www.appliedbiomath.com), the industry-leader in applying mechanistic modeling to drug research and development, today announced their participation in the upcoming American Conference on Pharmacometrics (ACoP) occurring October 15-18, 2017 in Fort Lauderdale, FL. Applied BioMath will be a conference sponsor, exhibitor, and poster presenter. Applied BioMath’s posters will highlight several examples of model-aided drug invention (MADI) by presenting case studies in immuno-oncology, osteoarthritis, and antibody-drug conjugates. More specifically, they will show:

Applied BioMath, LLC Announced as Major Sponsor and Presenter at PBSS Event in Boston, MA

Applied BioMath (www.appliedbiomath.com), the industry-leader in applying mechanistic modeling to drug research and development, today announced their participation in an upcoming quantitative systems pharmacology (QSP) event hosted by the Pharmaceutical and BioScience Society on September 29, 2017 in Boston, MA. Applied BioMath is the sole major sponsor of the day-long event as well as a presenter of two case studies in immuno-oncology and osteoarthritis.   

QSP Day 2017 Poster Prizes

Thank you to all of the presenters and attendees that made QSP DAY 2017 such a success!   We heard great scientific talks along with engaged questions and very busy poster and networking sessions.    It was a full house to hear leaders from industry and academia talk about their use of mathematical modeling in drug R&D.  The following student and post-doc poster presenters were awarded top honors and cash prizes!

Applied BioMath, LLC Welcomes Louis J. Latino, Jr. as Senior VP of Sales and Business Development

Applied BioMath, the industry-leader in applying mechanistic modeling to drug research and development, today announced that Louis J. Latino, Jr. is joining its team as Senior Vice President of Business Development.  In this role, Lou will lead the Applied BioMath business development team and continue to develop the company's growth strategy in the biotechnology and pharmaceutical industry.

Registration is open for next QSP-SB Industry and Academia Sympsoium

The QSP-SB Industry & Academia Symposium is a seminar series for presenting, learning, and discussing topics relevant to quantitative systems pharmacology (QSP) and systems biology (SB). The goal of this event is to foster an active community of industry and academic participants interested in these topics, and create a forum for sharing of successes and challenges.

Applied BioMath, LLC aids Tusk Therapeutics with preclinical candidate selection using Quantitative Systems Pharmacology Modeling

Applied BioMath, the industry-leader in applying mechanistic modeling to drug research and development, announced their collaboration with Tusk Therapeutics for quantitative systems pharmacology (QSP) modeling and analysis to enable preclinical candidate selection in immuno-oncology. Applied BioMath leveraged its proprietary mechanistic modeling platform to develop a QSP model of one of Tusk Therapeutics' targets and antibody candidates, then analyzed this model to identify optimal drug properties to aid preclinical candidate selection.

Applied BioMath, LLC To Present and Lead Workshop at Drug Development Boot Camp 2016

Applied BioMath (www.appliedbiomath.com), the industry-leader in applying mechanistic modeling to drug research and development, will present at Drug Development Boot Camp on November 16-17, 2016 at The Harvard Club in Boston, MA. This intensive two-day program, organized by Harvard University and Speid & Associates, allows executive level biotech and pharmaceutical scientists to share successes and challenges of the drug development process.

Applied BioMath, LLC Unveils the use of Mathematical Modeling in ADC therapeutics at the 7th Annual World ADC Conference

Updated 12/13/2016: Applied BioMath awarded Best Poster award at World ADC 2016!

Applied BioMath (www.appliedbiomath.com), the industry-leader in applying mechanistic modeling to drug research and development, today announced that they will deliver a presentation and poster at the 7th annual World ADC conference on the use of quantitative systems pharmacology (QSP) modeling to understand the pharmacokinetics (PK) of antibody drug conjugate (ADC) therapeutics.