Our Science

Filter Science by Keyword

Filter science by  disease  Clear filters

Collaboration
Publication
Quantitative modeling predicts competitive advantages of a next generation anti‐NKG2A therapy over monalizumab for the treatment of cancer
Collaboration with KSQ Therapeutics - Published in CPT: Pharmacometrics Systems Pharmacology
Disease Area
  • Immuno-oncology
Modality
  • mAb
View Details
Collaboration
Case Study
Semi-mechanistic Platform Model for Checkpoint Inhibitors
Collaboration with Pfizer
Disease Area
  • Immuno-oncology
Modality
  • mAb
View Details
Collaboration
Webinar
QSP Modeling for Dual Targeting Approaches for Two Immuno-oncology Therapeutics
Collaboration with Jounce - Presented by Dr. John M. Burke, Applied BioMath
Disease Area
  • Immuno-oncology
Modality
  • Bispecific
View Details
Publication
Mechanistic PKPD Models of Protein Therapeutics for Early Clinical Development
Published in AAPS Newsmagazine
Disease Area
  • Multiple
Modality
  • Multiple
View Details
Collaboration
Poster
Semi-mechanistic Platform Model for Individual Animal Responses to Checkpoint Inhibitors in a Syngeneic Mouse Model
Collaboration with Pfizer - Presented at AACR Annual Meeting 2019
Disease Area
  • Immuno-oncology
Modality
  • mAb
View Details
Collaboration
Poster
QSP Model of Cytokine mRNA Immunotherapy in Preclinical Melanoma Mouse Model
Collaboration with Sanofi - Presented at AACR Annual Meeting 2019
Disease Area
  • Immuno-oncology
Modality
  • Small Molecule
View Details
Poster
Inferring Target Occupancy from Fitting Nonlinear-PK Data with Mechanistic PKRO Model for Pembrolizumab
Best Abstract Award at AAPS 2018 PharmSci 360
Disease Area
  • Immuno-oncology
Modality
  • mAb
View Details
Collaboration
Poster
QSP Approaches Accelerate a PD-1 x TIM-3 Therapeutic in Immuno-oncology
Collaboration with Jounce
Disease Area
  • Immuno-oncology
Modality
  • Bispecific
View Details
Collaboration
Case Study
QSP Model of a Cytokine mRNA Immunotherapy
Collaboration with Sanofi
Disease Area
  • Immuno-oncology
Modality
  • Small Molecule
View Details
Publication
Model Firsts: How QSP can Pick the Right Dose for First-in-Human Trials
Published in BioCentury Innovations
Disease Area
  • Multiple
Modality
  • Multiple
View Details
Case Study
Inferring Target Occupancy
Disease Area
  • Immuno-oncology
Modality
  • mAb
View Details
Poster
Dynamic Target-Mediated Drug Disposition (TMDD)
Presented at AAPS 2018 PharmSci 360
Disease Area
  • Immuno-oncology
Modality
  • mAb
View Details