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Collaboration
Poster
Dose Selection for DuoBody®-PD-L1x4-1BB (GEN1046) Using a Semimechanistic Pharmacokinetics/Pharmacodynamics Model That Leverages Preclinical and Clinical Data
Collaboration with Genmab - Presented at SITC 2021
Disease Area
  • Immuno-oncology
Modality
  • Bispecific
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Collaboration
Poster
Prediction of systemic cytokine exposure in human after IV administration of oncolytic myxoma virus, using quantitative systems pharmacology modeling
Collaboration with OncoMyx Therapeutics - Presented at the American Association for Cancer Research, Annual Meeting 2021
Disease Area
  • Immuno-oncology
Modality
  • Small Molecule
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Publication
Mathematical Approaches for Predicting Risks Early-On in Drug R&D
Published in Pharma Tech Outlook Magazine
Disease Area
  • Multiple
Modality
  • Bispecific
  • mAb
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Collaboration
Publication
Quantitative modeling predicts competitive advantages of a next generation anti‐NKG2A therapy over monalizumab for the treatment of cancer
Collaboration with KSQ Therapeutics - Published in CPT: Pharmacometrics Systems Pharmacology
Disease Area
  • Immuno-oncology
Modality
  • mAb
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Collaboration
Case Study
Semi-mechanistic Platform Model for Checkpoint Inhibitors
Collaboration with Pfizer
Disease Area
  • Immuno-oncology
Modality
  • mAb
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Collaboration
Webinar
QSP Modeling for Dual Targeting Approaches for Two Immuno-oncology Therapeutics
Collaboration with Jounce - Presented by Dr. John M. Burke, Applied BioMath
Disease Area
  • Immuno-oncology
Modality
  • Bispecific
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Publication
Mechanistic PKPD Models of Protein Therapeutics for Early Clinical Development
Published in AAPS Newsmagazine
Disease Area
  • Multiple
Modality
  • Multiple
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Collaboration
Poster
Semi-mechanistic Platform Model for Individual Animal Responses to Checkpoint Inhibitors in a Syngeneic Mouse Model
Collaboration with Pfizer - Presented at AACR Annual Meeting 2019
Disease Area
  • Immuno-oncology
Modality
  • mAb
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Collaboration
Poster
QSP Model of Cytokine mRNA Immunotherapy in Preclinical Melanoma Mouse Model
Collaboration with Sanofi - Presented at AACR Annual Meeting 2019
Disease Area
  • Immuno-oncology
Modality
  • Small Molecule
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Poster
Inferring Target Occupancy from Fitting Nonlinear-PK Data with Mechanistic PKRO Model for Pembrolizumab
Best Abstract Award at AAPS 2018 PharmSci 360
Disease Area
  • Immuno-oncology
Modality
  • mAb
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Collaboration
Poster
QSP Approaches Accelerate a PD-1 x TIM-3 Therapeutic in Immuno-oncology
Collaboration with Jounce
Disease Area
  • Immuno-oncology
Modality
  • Bispecific
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Collaboration
Case Study
QSP Model of a Cytokine mRNA Immunotherapy
Collaboration with Sanofi
Disease Area
  • Immuno-oncology
Modality
  • Small Molecule
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