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Publication
Mathematical Approaches for Predicting Risks Early-On in Drug R&D
Published in Pharma Tech Outlook Magazine
Disease Area
  • Multiple
Modality
  • Bispecific
  • mAb
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Collaboration
Publication
Virtual clinical trial simulations for a novel KRASG12C inhibitor (ASP2453) in non-small cell lung cancer
Collaboration with Astellas Pharma - Published in CPT: Pharmacometrics Systems Pharmacology
Disease Area
  • Oncology
Modality
  • Small Molecule
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Collaboration
Publication
Model-Informed Drug Development of the Masked Anti-PD-L1 Antibody CX-072
Collaboration with CytomX Therapeutics - Published in Clinical Pharmacology & Therapeutics
Disease Area
  • Oncology
Modality
  • mAb
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Collaboration
Poster
Phase 1 Safety of ICOS Agonist Antibody JTX-2011 Alone and with Nivolumab in Advanced Solid Tumors
Collaboration with Jounce - Presented at ASCO Annual Meeting 2017
Disease Area
  • Oncology
Modality
  • mAb
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Publication
Mechanistic Quantitative Pharmacology Strategies for the Early Clinical Development of Bispecific Antibodies in Oncology
Published in Clinical Pharmacology & Therapeutics
Disease Area
  • Oncology
Modality
  • Bispecific
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Collaboration
Webinar
Translational Modeling Strategies to Predict Clinical Doses for CD3 Bispecific Molecules
Collaboration with Pfizer - Presented by Alison Betts, Applied BioMath
Disease Area
  • Oncology
Modality
  • Bispecific
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Publication
Mechanistic PKPD Models of Protein Therapeutics for Early Clinical Development
Published in AAPS Newsmagazine
Disease Area
  • Multiple
Modality
  • Multiple
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Poster
Computational Exploration of ADC Pharmacokinetics
Best Poster Award at World ADC 2016
Disease Area
  • Oncology
Modality
  • ADC
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Collaboration
Poster
Non-clinical Studies to Clinical Design Using QSP Model of T Cell Engaging Bispecifics
Collaboration with Pfizer - Presented at AAPS 2019 PharmSci 360
Disease Area
  • Oncology
Modality
  • Bispecific
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Collaboration
Poster
Modeling to Support Dose Justification for Anti-PD-L1 Clinical Candidate CK-301 in Oncology Patients
Collaboration with Checkpoint Therapeutics - Presented at SITC Annual Meeting 2019
Disease Area
  • Oncology
Modality
  • mAb
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Publication
Model Firsts: How QSP can Pick the Right Dose for First-in-Human Trials
Published in BioCentury Innovations
Disease Area
  • Multiple
Modality
  • Multiple
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Collaboration
Publication
QSP Model of a Masked, Tumor-Activated Antibody
Collaboration with CytomX Therapeutics - Published in CPT: Pharmacometrics & Systems Pharmacology
Disease Area
  • Oncology
Modality
  • mAb
View Details