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Publication
Mathematical Modeling and the Monkey King: Use of modeling for more efficient NHP study design
Disease Area
  • Multiple
Modality
  • Multiple
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Publication
Early Feasibility Assessment: A Method for Accurately Predicting Biotherapeutic Dosing to Inform Early Drug Discovery Decisions
Disease Area
  • Multiple
Modality
  • Multiple
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Publication
Getting the Dose Right in Oncology
By: Dr. Alison Betts, Vice President of Scientific Collaborations and Fellow of Modeling & Simulation of Applied BioMath
Disease Area
  • Oncology
  • Immuno-oncology
Modality
  • Multiple
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Collaboration
Poster
A computational semi-mechanistic pharmacology model of ATG-101, a PD-L1/4-1BB bispecific antibody for treatment of solid tumors
Collaboration with Antengene - Presented at SITC 2021
Disease Area
  • Oncology
Modality
  • Bispecific
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Publication
Mathematical Approaches for Predicting Risks Early-On in Drug R&D
Published in Pharma Tech Outlook Magazine
Disease Area
  • Multiple
Modality
  • Bispecific
  • mAb
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Collaboration
Publication
Virtual clinical trial simulations for a novel KRASG12C inhibitor (ASP2453) in non-small cell lung cancer
Collaboration with Astellas Pharma - Published in CPT: Pharmacometrics & Systems Pharmacology
Disease Area
  • Oncology
Modality
  • Small Molecule
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Collaboration
Publication
Model-Informed Drug Development of the Masked Anti-PD-L1 Antibody CX-072
Collaboration with CytomX Therapeutics - Published in Clinical Pharmacology & Therapeutics
Disease Area
  • Oncology
Modality
  • mAb
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Collaboration
Poster
Phase 1 Safety of ICOS Agonist Antibody JTX-2011 Alone and with Nivolumab in Advanced Solid Tumors
Collaboration with Jounce - Presented at ASCO Annual Meeting 2017
Disease Area
  • Oncology
Modality
  • mAb
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Publication
Mechanistic Quantitative Pharmacology Strategies for the Early Clinical Development of Bispecific Antibodies in Oncology
Published in Clinical Pharmacology & Therapeutics
Disease Area
  • Oncology
Modality
  • Bispecific
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Collaboration
Webinar
Translational Modeling Strategies to Predict Clinical Doses for CD3 Bispecific Molecules
Collaboration with Pfizer - Presented by Alison Betts, Applied BioMath
Disease Area
  • Oncology
Modality
  • Bispecific
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Publication
Mechanistic PKPD Models of Protein Therapeutics for Early Clinical Development
Published in AAPS Newsmagazine
Disease Area
  • Multiple
Modality
  • Multiple
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Poster
Computational Exploration of ADC Pharmacokinetics
Best Poster Award at World ADC 2016
Disease Area
  • Oncology
Modality
  • ADC
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