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Collaboration
Poster
Dose Selection for DuoBody®-PD-L1x4-1BB (GEN1046) Using a Semimechanistic Pharmacokinetics/Pharmacodynamics Model That Leverages Preclinical and Clinical Data
Collaboration with Genmab - Presented at SITC 2021
Disease Area
  • Immuno-oncology
Modality
  • Bispecific
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Collaboration
Poster
A computational semi-mechanistic pharmacology model of ATG-101, a PD-L1/4-1BB bispecific antibody for treatment of solid tumors
Collaboration with Antengene - Presented at SITC 2021
Disease Area
  • Oncology
Modality
  • Bispecific
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Publication
Mathematical Approaches for Predicting Risks Early-On in Drug R&D
Published in Pharma Tech Outlook Magazine
Disease Area
  • Multiple
Modality
  • Bispecific
  • mAb
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Publication
Mechanistic Quantitative Pharmacology Strategies for the Early Clinical Development of Bispecific Antibodies in Oncology
Published in Clinical Pharmacology & Therapeutics
Disease Area
  • Oncology
Modality
  • Bispecific
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Collaboration
Webinar
Translational Modeling Strategies to Predict Clinical Doses for CD3 Bispecific Molecules
Collaboration with Pfizer - Presented by Alison Betts, Applied BioMath
Disease Area
  • Oncology
Modality
  • Bispecific
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Collaboration
Webinar
QSP Modeling for Dual Targeting Approaches for Two Immuno-oncology Therapeutics
Collaboration with Jounce - Presented by Dr. John M. Burke, Applied BioMath
Disease Area
  • Immuno-oncology
Modality
  • Bispecific
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Publication
Mechanistic PKPD Models of Protein Therapeutics for Early Clinical Development
Published in AAPS Newsmagazine
Disease Area
  • Multiple
Modality
  • Multiple
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Collaboration
Poster
QSP Approaches Accelerate a PD-1 x TIM-3 Therapeutic in Immuno-oncology
Collaboration with Jounce
Disease Area
  • Immuno-oncology
Modality
  • Bispecific
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Collaboration
Poster
Non-clinical Studies to Clinical Design Using QSP Model of T Cell Engaging Bispecifics
Collaboration with Pfizer - Presented at AAPS 2019 PharmSci 360
Disease Area
  • Oncology
Modality
  • Bispecific
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Collaboration
Webinar
Model-Based Approach to Design Bi-Specific Modalities in Early Discovery
Collaboration with Sanofi - Presented by Dr. Jennifer Fretland, Sanofi
Disease Area
  • Inflammation and Immunology
Modality
  • Bispecific
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Publication
Model Firsts: How QSP can Pick the Right Dose for First-in-Human Trials
Published in BioCentury Innovations
Disease Area
  • Multiple
Modality
  • Multiple
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Case Study
Early Feasibility Assessment
Disease Area
  • Multiple
Modality
  • Bispecific
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