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Publication
Mathematical Modeling and the Monkey King: Use of modeling for more efficient NHP study design
Disease Area
  • Multiple
Modality
  • Multiple
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Publication
Early Feasibility Assessment: A Method for Accurately Predicting Biotherapeutic Dosing to Inform Early Drug Discovery Decisions
Disease Area
  • Multiple
Modality
  • Multiple
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Publication
Getting the Dose Right in Oncology
By: Dr. Alison Betts, Vice President of Scientific Collaborations and Fellow of Modeling & Simulation of Applied BioMath
Disease Area
  • Oncology
  • Immuno-oncology
Modality
  • Multiple
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Collaboration
Publication
Quantitative Systems Pharmacology Modeling Provides Insight into Inter-mouse Variability of Anti-CTLA4 Response
Collaboration with Pfizer - Published in CPT: Pharmacometrics & Systems Pharmacology
Disease Area
  • Immuno-oncology
Modality
  • mAb
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Webinar
[Webinar] De-risking Bispecifics Early-on: How tight is too tight? How weak is too weak?
Disease Area
  • Other
Modality
  • Other
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Collaboration
Publication
Quantitative systems pharmacology model for Alzheimer’s disease to predict the effect of aducanumab on brain amyloid
Collaboration with Biogen - Published in CPT: Pharmacometrics Systems Pharmacology
Disease Area
  • Neuroscience
Modality
  • mAb
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Publication
Two heads are better than one: current landscape of integrating QSP and machine learning
Published in the Journal of Pharmacokinetics and Pharmacodynamics
Disease Area
  • Other
Modality
  • Other
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Collaboration
Poster
Dose Selection for DuoBody®-PD-L1x4-1BB (GEN1046) Using a Semimechanistic Pharmacokinetics/Pharmacodynamics Model That Leverages Preclinical and Clinical Data
Collaboration with Genmab - Presented at SITC 2021
Disease Area
  • Immuno-oncology
Modality
  • Bispecific
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Collaboration
Poster
A computational semi-mechanistic pharmacology model of ATG-101, a PD-L1/4-1BB bispecific antibody for treatment of solid tumors
Collaboration with Antengene - Presented at SITC 2021
Disease Area
  • Oncology
Modality
  • Bispecific
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Collaboration
Poster
Prediction of systemic cytokine exposure in human after IV administration of oncolytic myxoma virus, using quantitative systems pharmacology modeling
Collaboration with OncoMyx Therapeutics - Presented at the American Association for Cancer Research, Annual Meeting 2021
Disease Area
  • Immuno-oncology
Modality
  • Small Molecule
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Webinar
[Webinar] A Systems Model of Gene Therapy for Sickle Cell Disease
Disease Area
  • Rare Disease
Modality
  • Other
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Publication
Mathematical Approaches for Predicting Risks Early-On in Drug R&D
Published in Pharma Tech Outlook Magazine
Disease Area
  • Multiple
Modality
  • Bispecific
  • mAb
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