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Collaboration
Poster
Dose Selection for DuoBody®-PD-L1x4-1BB (GEN1046) Using a Semimechanistic Pharmacokinetics/Pharmacodynamics Model That Leverages Preclinical and Clinical Data
Collaboration with Genmab - Presented at SITC 2021
Disease Area
  • Immuno-oncology
Modality
  • Bispecific
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Collaboration
Poster
A computational semi-mechanistic pharmacology model of ATG-101, a PD-L1/4-1BB bispecific antibody for treatment of solid tumors
Collaboration with Antengene - Presented at SITC 2021
Disease Area
  • Oncology
Modality
  • Bispecific
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Collaboration
Poster
Prediction of systemic cytokine exposure in human after IV administration of oncolytic myxoma virus, using quantitative systems pharmacology modeling
Collaboration with OncoMyx Therapeutics - Presented at the American Association for Cancer Research, Annual Meeting 2021
Disease Area
  • Immuno-oncology
Modality
  • Small Molecule
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Webinar
[Webinar] A Systems Model of Gene Therapy for Sickle Cell Disease
Disease Area
Modality
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Publication
Mathematical Approaches for Predicting Risks Early-On in Drug R&D
Published in Pharma Tech Outlook Magazine
Disease Area
  • Multiple
Modality
  • Bispecific
  • mAb
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Collaboration
Publication
Virtual clinical trial simulations for a novel KRASG12C inhibitor (ASP2453) in non-small cell lung cancer
Collaboration with Astellas Pharma - Published in CPT: Pharmacometrics & Systems Pharmacology
Disease Area
  • Oncology
Modality
  • Small Molecule
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Collaboration
Publication
A systems pharmacology model for gene therapy in sickle cell disease
Collaboration with CSL Behring - Published in CPT: Pharmacometrics Systems Pharmacology
Disease Area
  • Rare Disease
Modality
  • Other
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Webinar
De-risking Biologics: T-Cell Engager and Antibody-Protein Fusion Bispecific Case Studies
Disease Area
  • Other
Modality
  • Other
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Publication
De-Risking Drug Discovery with Applied BioMath Assess™ An Early Feasibility Assessment Tool for Biotherapeutics
Disease Area
  • Other
Modality
  • Other
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Publication
Systematic in silico analysis of clinically tested drugs for reducing amyloid-beta plaque accumulation in Alzheimer's disease
Published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Disease Area
  • Neuroscience
Modality
  • Small Molecule
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Webinar
Applied BioMath Assess™ - An Early Feasibility Assessment Tool for Biotherapeutics
Disease Area
  • Other
Modality
  • Other
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Case Study
Early Feasibility Assessment of an anti-TNF Biotherapeutic
Disease Area
Modality
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