QSP Summit

Thursday, November 5, 2020
Virtual | 9am-5pm ET

About the Event

qsp summit

The Quantitative Systems Pharmacology (QSP) Summit is an annual meeting dedicated to fostering an active community of industry and academic participants interested in topics relevant to QSP. In its fourth year, the QSP Summit features talks from key industry and academic researchers and a poster session with awards. No fee is required.

Poster Awards

Congratulations to the poster award winners:

1st Place: Maria Jesus Munoz-Lopez, PhD Candidate at University of Pennsylvania
"Stochastic modeling of cell bleb-driven migration"

2nd Place: Sourish Chakravarty, Postdoctoral Associate at MIT
"Development and validation of a closed-loop anesthesia delivery system in a non-human primate model"

3rd Place: Dongheon Lee, Postdoctoral Associate at Duke University
"A Hybrid Modeling Approach to Model Dynamics of a Partially Known Signaling Pathway"

QSP Summit 2019

Agenda

09:00 AM	Opening remarks John Burke, PhD Co-Founder, President & CEO at Applied BioMath
09:15 AM	"A virtual population (VPop) development workflow applied to immuno-oncology quantitative systems pharmacology models (I-O QSP platforms)" Yougan Cheng, PhD Associate Director, QSP Lead - Oncology/Immuno-oncology at Bristol Myers Squibb
09:45 AM	"A quantitative systems pharmacology model for Amyloid-β pathway to predict effect of Aducanumab on SUVR change" Lin Lin, PhD Senior Scientist, Pharmacometrics at Biogen
10:15 AM	Break
10:30 AM	"Cell-to-cell heterogeneity and QSP: How do we identify and target macrophage subsets?" Kathryn Miller-Jensen, PhD Associate Professor of Biomedical Engineering at Yale University
11:00 AM	"QSP modeling to accelerate the down-selection and development of novel TB drug regimens" Chanchala Kaddi, PhD Senior Modeler at Bill & Melinda Gates Medical Research Institute
11:30 AM	"Modeling avidity to guide optimization of bispecific molecules" David Flowers, PhD Principal Scientist at Applied BioMath
12:00 PM	Break
01:15 PM	"Reverse translation in Quantitative Systems Pharmacology" Panagiota (Pegy) Foteinou, PhD Director, QSP - Immunology at Bristol Myers Squibb
01:45 PM	"QSP modeling applications in heart failure" Anna Sher, PhD, MD Principal Scientist at Pfizer
02:15 PM	Break
02:45 PM	Lightning talks "Role of IL-23 suppression in psoriasis - insights from meta-analysis of clinical data" Georgi Kapitanov, PhD, Principal Scientist at Pfizer "Computational analysis of combination therapy of bispecific T cell engagers (BiTE) with anti-programmed cell death-1 (PD1) inhibitor for the treatment of hematological malignancies" Florencio Serrano Castillo, PhD, Scientist at Amgen "A hybrid modeling approach to model dynamics of a partially known signaling pathway" Dongheon Lee, PhD, Postdoctoral Associate at Duke University "Stochastic modeling of cell bleb-driven migration" Maria Jesus Munoz-Lopez, PhD Candidate at University of Pennsylvania "Improving the accuracy and precision of volume of distribution predictions for highly lipophilic compounds from tissue-composition based PBPK models" Shibin Mathew, PhD, Senior Scientist at Pfizer
04:00 PM	Break
04:15 PM	"Choreographing an immune response by targeting novel macrophage targets" Tatiana Novobrantseva, PhD Co-founder and CSO at Verseau Therapeutics
04:45 PM	Closing remarks and poster awards
05:00 PM	Event concludes

Speakers

Yougan Cheng, PhD, Associate Director, QSP Lead Oncology/Immuno-oncology at Bristol Myers Squibb
Panagiota Foteinou, PhD, Research Fellow/Director - QSP Immunology at Bristol Myers Squibb
Chanchala Kaddi, PhD, Senior Modeler at Bill & Melinda Gates Medical Research Institute
Lin Lin, PhD, Senior Scientist, Pharmcometrics at Biogen
Kathryn Miller-Jensen, PhD, Associate Professor of Biomedical Engineering at Yale University
Tatiana Novobrantseva, PhD, Co-founder and CSO at Verseau Therapeutics
Anna Sher, PhD, MD, Principal Scientist at Pfizer

Questions?

Contact Renee at rfisher@appliedbiomath.com.