Science Advisory Board

Mike Yaffe, MD PhD

David H. Koch Professor of Biology and Biological Engineering,
Massachusetts Institute of Technology

Director of Clinical Outreach,
Koch Institute for Integrative Cancer Research

Senior Associate Member,
Broad Institute

Attending Surgeon,
Beth Israel Deaconess Medical Center

Bruce Tidor, PhD

Professor of Biological Engineering and Computer Science,

Massachusetts Institute of Technology

Werner Meier

Former Vice President of Biologics Drug Discovery, Biogen Inc.

Joseph Loscalzo, MD, PhD

Chair of the Department of Medicine and Physician-in-Chief at Brigham and Women’s Hospital (BWH)

Hersey Professor of the Theory and Practice of Medicine at Harvard Medical School (HMS)

Doug Lauffenburger, PhD (SAB Chair)

Head of the Department of Biological Engineering,

Massachusetts Institute of Technology

Ford Professor of Biological Engineering, Chemical Engineering and Biology

Joshua Apgar, PhD

Before co-founding Applied BioMath, Josh was a Principal Scientist in the Systems Biology Group of the Department of Immunology and Inflammation at Boehringer Ingelheim Pharmaceuticals. His work leveraged physics-based models to: translate in vitro and in vivo data, assess target feasibility, understand drug mechanism of action, and predict human doses. The ultimate goal of this work was to reduce late stage attrition in drug development through a deep and quantitative interrogation of drug pharmacology and disease pathophysiology.

John M. Burke, PhD

Dr. Burke’s BS and MS are in Applied Mathematics from the University of Massachusetts, Lowell, in 1993 and 1995, respectively. His PhD degree is in Applied Mathematics from Arizona State University in 2003. His research interests include singularly and randomly perturbed differential equations, bifurcation theory, and applying dynamical systems theory to study and understand how cells and tissues make decisions in humans, and human disease. Prior to co-founding Applied BioMath, Dr. Burke joined Boehringer Ingelheim in 2008 as Associate Director, Head of Systems Biology.