Jaehee received her PhD in Biomedical Science from Icahn School of Medicine at Mount Sinai in 2019. As a part of her thesis work, she developed a computational pipeline for gene expression based, personalized predictions of targeted cancer therapeutics induced cardiotoxicity. This computational pipeline takes in RNAseq data and extracts relevant gene expression changes and uses it as an input to mechanistic models to simulate patient specific responses in hypertrophy, cardiac death, arrhythmia, and contractile failure. Jaehee has interned with health analytics group at IBM T.J Watson Research Center in 2016 where she built a data-driven, personalized dose prediction model for vancomycin by applying machine learning algorithms on electronic medical records.

 

Scientist Spotlight

May 2020

What is your role at Applied BioMath?

“I am a modeler. I build QSP models and run analyses to support on-going projects.”

What do you love most about working here?

“I love how kind everyone is at Applied BioMath. They are all incredibly intelligent and kind—that is a rare combination. I also enjoy the opportunity to learn about different therapeutic types.”

What is the most rewarding part of your job?

“It’s very gratifying to contribute to the drug development process and improve the health of others.”

What was your main area of focus during your academics?

“I studied cancer therapeutic induced cardiac side effects. Specifically, I worked on developing a computational pipeline that can generate dynamical simulations based on the gene expression data to predict possible cardiac side effects in a patient specific manner.”

What made you get into the field of life sciences?

“I always enjoyed science—biology and chemistry in particular. I think it was more of a natural choice for me to go into life science.” 

What do you like to do in your spare time?

“Lately, I have been playing VR games or reading books.”

Do you have a motto or personal mantra you live by?

"Your life is God's gift to you, and what you do with it is your gift to God. I try to live my life with this phrase in mind, so I remember to enjoy every day.”

If you won the lottery, what is the first thing you would do?

“I would want to travel all over the world, especially to countries in Europe and Southeast Asia!”

What is a random fun fact about yourself?

“I really enjoy painting—more specifically, portrait painting. You can learn so much about a person’s past and their life stories from their face. Every wrinkle and line depicts their character. I’m hoping to focus more on my painting during my retirement years.”

What inspires you every day?

“Learning inspires me every day. I love to learn new things, so I can build my knowledge and one day become an expert in a topic of study.”

Jaehee

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