Theresa is a clinical pharmacologist and pharmacometrician with nearly 10 years of experience in pharma and biotech, supporting small molecule and biologics development.  Prior to joining Applied Biomath, Theresa held positions in clinical pharmacology and pharmacometrics at Merck, Amgen, and CSL Behring. Most recently, Theresa led the pharmacometrics group at CSL Behring.  She oversaw modeling and simulation activities across the portfolio, facilitating rational, quantitative approaches to decision-making from preclinical development through submission and lifecycle management.  Theresa also has extensive experience in clinical pharmacology, working on cross-functional project teams guiding drug development across a range of therapeutic areas, including immuno-oncology, infectious diseases, neuroscience, and rare diseases.  With her combination of technical skills and clinical pharmacology experience, she is well-positioned to develop effective, fit-for-purpose modeling and simulation strategies that address clinically relevant questions, enable decision-making, and facilitate positive regulatory interactions throughout the development process. 

Theresa received her PhD in Chemical Engineering from the University of California Santa Barbara, where she developed a systems pharmacology model to describe tau pathophysiology and identify therapeutic targets for neurological disorders like Alzheimer’s disease.  She received her BS degree in Chemical Engineering from Lehigh University.


Scientist Spotlight

January 2021

What is your role at Applied BioMath?

"I am the Director of Pharmacometrics and Clinical Pharmacology. My job is to provide clinical pharmacology and pharmacometrics support to clients from the Pre-IND phase all the way to life cycle management." 

What do you love most about working here?

"The culture is fantastic, and the people are very scientifically minded. Everyone is so open, friendly, and welcoming. I feel very valued and appreciated as an employee even though I have only been here for a couple months. I also love how the founders are very invested in the community. Charitable giving is very important to them, and that is really impressive to me." 

What is the most rewarding part of your job?

"Making impactful contributions and having a significant affect on drug development decisions. For instance, helping to select an appropriate dose, getting the dose right, and then having the study come back and show that the dose worked and was safe and efficacious is really satisfying." 

What was your specialty prior to coming to ABM?

"Clinical pharmacology and pharmacometrics."

What made you get into the field of life sciences?

"I really wanted to do something to help people."

What do you like to do in your spare time?

"I love to read, bike, and hike with my dog. I also enjoy rock climbing, hot yoga, and snowboarding. "

If you won the lottery, what is the first thing you would do?

"I would want to go to Nepal and hike around the Himalayas. That is my dream trip."

What is something most people don’t know about you?

"I’m a huge Harry Potter fan. I know everything about Harry Potter that I think there is to know."

What inspires you every day?

"All the interesting scientific work that is ultimately going to help people. It is so cool to see all the advances in cancer treatment and getting to be partially involved with that is really motivating. It is motivating to see the difference you can make in people’s lives."



Key Research

  • A systems pharmacology model for gene therapy in sickle cell disease

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