Quantitative Systems Pharmacology (QSP) Summit Cambridge 2024
About the Event
The Quantitative Systems Pharmacology (QSP) Summit is a free conference dedicated to fostering an active community of industry and academic participants interested in topics relevant to QSP. In its seventh year, the QSP Summit is a one-day event featuring talks from key industry and academic researchers, a poster session, and networking time with peers.
Date: May 1, 2024
Time: 9am - 5pm ET
Venue: Le Meridien Boston Cambridge, 20 Sidney Street, Cambridge, MA 02139
Speakers
Alison Betts, PhD - Global Head of DMPK and Modeling, Preclinical & Translational Sciences at Takeda
Joe Bender, PhD - Computational Lab Director at United Therapeutics
Giuseppe Ciaramella, PhD - President at Beam Therapeutics
Victoria Etges Helfer, PhD - Postdoctoral Fellow at UNC/GSK
Piet van der Graaf, PharmD, PhD - SVP, Head of QSP at Certara
Linda Griffith, PhD - School of Engineering Professor of Teaching Innovation, Departments of Biological and Mechanical Engineering, Director - Center for Gynepathology Research at MIT
Jeff Kearns, PhD - Director, Translational Modeling & Simulation at Novartis Biomedical Research
Krina Mehta, MSc - Director, Pharmacometrics at Kyowa Kirin
Dominic Whittaker, PhD - Investigator, QSP at GSK
Agenda
| Start Time (ET) | Event |
| 9:00 AM | Breakfast and registration |
| 9:30 AM | Opening remarks |
| 9:45 AM | Piet van der Graaf, PharmD, PhD "QSP 2.0: Industrializing the Impact of Mechanistic Modeling Across the R&D Spectrum" |
| 10:15 AM | Alison Betts, PhD "Accelerating Early Development of Bispecifics and ADCs for Oncology Using QSP" |
| 10:45 AM | Break and poster session |
| 11:15 AM | Krina Mehta, MSc "Leveraging QSP to Shape the Strategy for Early Phase Clinical Development in Immuno-Oncology: CD40 Agonistic Bispecific Antibody as a Case Study" |
| 11:45 AM | Joe Bender, PhD "Evaluation of Combination Therapy Regimens in a Pulmonary Hypertension QSP Model" |
| 12:15 PM | Lunch and poster session |
| 1:00 PM | Linda Griffith, PhD "Building Physiomimetic In Vitro Models of Chronic Inflammatory Diseases" |
| 1:30 PM | Jeff Kearns, PhD "Modeling with a Vision: Translational Insights from Discovery to Late-stage Development in Ophthalmology" |
| 2:00 PM | Break and poster session |
| 2:30 PM | Victoria Etges Helfer, PhD Dominic Whittaker, PhD "Development of a QSP Model for HIV Viral Dynamics to Identify Optimal Combination Therapies" |
| 3:00 PM | Pino Ciaramella, PhD "Base Editing Next Generation in Gene Editing" |
| 3:30 PM | Break and poster session |
| 4:00 PM | Roundtable Discussion Apgar (Applied BioMath), Betts (Takeda), Kearns (Novartis Biomedical Research) Moderated by John Burke, PhD |
| 4:45 PM | Closing remarks and poster awards |
| 5:00 PM | QSP Summit concludes |
