Publications

Albeck, J. G., Burke, J. M., Spencer, S. L., Lauffenburger, D. A., and Sorger, P. K. (2008). Modeling a snap-action, variable-delay switch controlling extrinsic cell death. PLoS Biology.
PMID:19053173

Gruenbaum, L.M., Schwartz, R., Woska, J., DeLeon, R., Peet, G. Warren, T., Capolino, A., Morelock, M., Mara, L. and Pargellis, C.A. (2008). Inhibition of pro-inflammatory cytokine production by the dual p38/JNK inhibitor BIRB796 correlates with the inhibition of p38 signaling. Biochemical Pharmacology.
PMID: 19027720

Albeck, J. G., Burke, J. M., Aldridge, B. B., Zhang, M., Lauffenburger, D. A., and Sorger, P. K. (2008). Quantitative analysis of pathways controlling extrinsic apoptosis in single cells. Molecular Cell.
PMID:18406323

Goldberg, D. R., Choi, Y., Cogan, D., Corson, M., Gao, A., Gruenbaum, L.M., Joseph, D., Kasham, M.A., Mara, L., Miller, C., Moss, N., Netherton, M., Pargellis, C. P., Pelletier, J., Sellati, R., Skow, D., Torcellini, C., Tseng, C., Wang, J., Wasti, R., Werneburg, B., Wu, J. P. and Xiong, Z. (2008). Pyrazinoindolone Inhibitors of MAPKAP-K2. Bioorganic & Medicinal Chemistry.
PMID: 18221871

Apgar, J. F., Toettcher, J. E., Endy, D., White, F. M., and Tidor, B. (2008). Stimulus design for model selection and validation in cell signaling. PLoS Computational Biology.
PMID:18282085

Wilkins, AK, Barton, PI, Tidor, B (2007). The Per2 negative feedback loop sets the period in the mammalian circadian clock mechanism. PLoS Comput. Biol.
PMID: 18085817

Aldridge, B., Burke, J. M., Lauffenburger, D., and Sorger, P. (2006). Physicochemical modelling of cell signalling pathways. Nature Cell Biology 8, 1195-1203.
PMID:17060902

Hendriks, B.S., Cook, J., Burke, J.M., Beusmans, J.M., Lauffenburger, D.A., de Graaf, D. (2006). Computational modelling of ErbB family phosphorylation dynamics in response to transforming growth factor alpha and heregulin indicates spatial compartmentation of phosphatase activity.. Systems Biology (Stevenage).
PMID:16983832

Rabenstein, R.L. Addy, N.A. Caldarone, B.J. Asaka, Y. Gruenbaum, L.M., Peters, L.L. Gilligan, D.M., Fitzsimonds, R.M. and Picciotto, M.R (2005). Impaired synaptic plasticity and learning in mice lacking beta-adducin, an actin-regulating protein. The Journal of Neuroscience.
PMID: 15728854

Gruenbaum, L.M., Gilligan, D.M., and Carew, T.J (2003). Identification and characterization of Aplysia adducin, an Aplysia cytoskeletal protein homologous to mammalian adducins: increased phosphorylation at a protein kinase C consensus site during long-term synaptic facilitation. The Journal of Neuroscience.
PMID: 12684453

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