ACoP14
Applied BioMath Conference Presence
Posters:
- Effects of Tissue Targeting Bispecifics on Therapeutic Window
- Presenter: Sasha Shirman, PhD, Senior Scientist, Modeling
- Anti-PD-1 vs. Anti-PD-L1 Antibodies - Insights From QSP-Based Meta-Analysis
- Presenter: Carter Johnson, PhD, Senior Scientist, Modeling
- A quantitative systems pharmacology model describing the cellular kinetic-pharmacodynamic relationship for a live biotherapeutic product to support microbiome drug development
- Presenter: Marissa Renardy, PhD, Principal Scientist
- PK/PD Modeling of Anti-Circumsporozoite Protein (CSP) Antibodies to Predict Dosing Requirements for Malaria Prevention
- Presenter: Joshuaine Grant, MSc, MBA, Director of Modeling
- Early Feasibility Assessment: A Method for Accurately Predicting Biotherapeutic Dosing to Inform Early Drug Discovery Decisions with Applied BioMath Assess™
- Presenter: Debbie Flusberg, PhD, Principal Scientist
Pre-Conference Workshop:
Day and Time: Sunday, November 5th, from 1:00 - 5:00pm ET
Workshop Title: Practical Application of MID3 to Inform Early Drug Discovery Decisions Using Applied BioMath Assess™
Workshop Instructors:
- Joshua F. Apgar, PhD, Co-Founder and CSO of Applied BioMath
- John Burke, PhD, Co-Founder, President, and CEO of Applied BioMath
- Andrew Matteson, PhD, Director of Product at Applied BioMath
Workshop Outline:
The workshop will be divided into three, one-hour sessions.
Session 1: Provide a deep understanding of the Early Feasibility Assessment (EFA) methodology and how it can be used to inform early drug discovery decisions.
Session 2: Explore an EFA case study based upon a complex biotherapeutics drug. Participants will break into small teams to implement an EFA for their target. Using provided web based software, models, and literature, teams will be expected to select an appropriate model, parameterize it with data from the provided literature, and analyze the model to answer their specific questions. Experts will be available to help participants.
Session 3: Teams will present the conclusions of their assessment to the group, and their recommendation for the program. The organizers will then present an analysis for discussion. Participants will discuss the challenges of implementing EFA and the potential opportunities for EFA and MID3 more broadly to have impact at their organization.