Each model in the Cell Engager Model Pack includes a mechanism of action diagram and a pharmacology diagram (Figure 1) with model parameters and their nominal values (Figure 2).
Figure 1: Model Diagrams
Created in BioRender.com
Figure 2: Model Parameters
Each model in Applied BioMath Assess™ Cell Engager Model Pack has a unique set of parameters, a sample of which is shown here, based on the model pharmacology and number of compartments. More details on the full list of parameters are available upon request. In the app, each parameter contains a default value based on expansive literature searches and references.
Additional Model Packs
Biotherapeutic Model Pack: 18 models covering 9 common pharmacologies.