AAPS PharmSci 360

Event Details:

October 22nd - 25th | Orlando, FL 

Applied BioMath Presence:

Presentations

Tuesday, October 24th | 9:30 - 10:30am ET

Title: Evolving Clinical Pharmacology and Translational PK/PD Approaches for New Modalities 

Presenter: Joshua Apgar, PhD, Co-Founder and CSO

Fei Hua, PhD, who is a member of the Scientific Programming Committee for the Preclinical and Translational Sciences Track, will moderate multiple presentations, including:

  • Speaker Spotlight: Advances in Predictive Biomarkers for Drug Development on Monday, October 23rd from 2:30-3:30pm
  • Keynote: Navigating Project Optimus: Use of Modeling and Simulation to Inform Dosing Strategies in Oncology on Tuesday, October 24th from 1:30-2:30pm
  • Keynote: Predictive Drug Discovery Platforms on Wednesday, October 25th from 1:30-2:30pm
  • Hot Topic: Understanding Data Needs for AI/ML Approaches During Preclinical Development on Wednesday, October 25th from 3:00-4:00pm


Posters

Monday, October 23rd from 12:30 - 1:30pm ET

Title: Using a Semi-Mechanistic Model to Predict Efficacious Dosing Regimens and Optimal Drug Design Properties for a LNP-Delivered mRNA UGT1A1 Replacement Therapy in Crigler-Najjar Syndrome Type 1 Patients

Presenter: Jamie Nosbisch, PhD, Principal Scientist

 

Monday, October 23rd from 11:30am - 12:30pm ET

Title: A Next Generation Mathematical Model for the In Vitro to Clinical Translation of T-Cell Engagers

Presenter: Fei Hua, PhD, Vice President of Modeling and Simulation Services