Immuno-Oncology Summit

Event Details

October 12th - 14th, 2022 | Boston

Applied BioMath Presence

Presentation: The Use of Model-Informed Drug Discovery and Development for the Design of Biotherapeutics in Immuno-oncology

Presenter: John Burke, PhD, Co-Founder, President, and CEO of Applied BioMath

Presentation Time: Wednesday, October 12th at 2:35pm ET

Abstract: Computational tools are increasingly used to aid in the design of biotherapeutics. This presentation will discuss three case studies where Model-informed Drug Discovery and Development was used to: 

  • Predict systemic cytokine exposure in human after IV administration of an oncolytic myxoma virus

  • Model GITR-mediated T-cell dynamics in Mouse Tumor Micro Environment

  • Provides Insight into Inter-mouse Variability of Anti-CTLA4 Response