Applied BioMath, LLC to Sponsor and Present at FierceBiotech Drug Development Forum

Applied BioMath (, the industry-leader in applying mechanistic modeling to drug research and development, today announced their participation in FierceBiotech’s second Drug Development Forum occurring September 25-27, 2017 in Boston, MA. Applied BioMath will be a sponsor as well as presenter at the event.

John Burke, PhD, Co-Founder, President and CEO will present a talk titled “Model Aided Drug Invention Case Studies: Quantitative Modeling and Simulation Approaches Driving Critical Decisions from Research through Clinical Trials.” Model Aided Drug Invention (MADI) is a mathematical modeling and engineering approach to translational medicine, which includes mechanistic PKPD and systems pharmacology, that aims to quantitatively integrate knowledge about therapeutics with an understanding of its mechanism of action in the context of human disease mechanisms. Dr. Burke’s discussion will analyze:

  • The use of MADI to de-risk projects, accelerate development of best-in-class therapeutics, and reduce late-stage attrition rates.
  • Biological understanding to improve lead generation, clinical candidate selection, and clinical trial go/no go decisions.
  • Case studies showing how MADI efforts accelerate drug discovery and development, and impact critical decisions in the continuum from preclinical exploration to clinical research.

“We are excited to participate in the Fierce Drug Development Forum for the first time this fall,” said John Burke, PhD, Co-Founder, President and CEO of Applied BioMath. “The MADI case studies in the presentation are just a few of many examples we have where our participation in a project has resulted in helping industry save money, accelerated timelines, and made better therapeutics, ultimately improving patients’ lives.”

Additionally this fall, Applied BioMath is participating in the World Bispecific Summit, a Boston PBSS Minisymposium, and the American Conference on Pharmacometrics (ACoP). For more information about Applied BioMath, please visit

About Applied BioMath

Applied BioMath (, the industry-leader in applying mechanistic modeling to drug research and development, helps biotechnology and pharmaceutical companies answer complex, critical Go/No-go decisions in R&D.    Applied BioMath leverages biology, proprietary mathematical modeling and analysis technology, high-performance computing, and decades of industry experience to help groups better understand their candidate, its best-in-class parameters, competitive advantages, and the best path forward.   Our involvement shortens project timelines, lowers cost, and increases the likelihood of a best-in-class drug.  We provide clarity to complex situations, answer otherwise unanswerable questions, and our approach, when validated in the clinic, is 10x more accurate than traditional methodologies.

Applied BioMath and the Applied BioMath logo are trademarks of Applied BioMath, LLC.

Press contact:

Kristen Zannella